HOME > Public Health News > Sex Hormones Linked to Metabolism, Genetic Study :: Manufacturer of Eleotin – Eastwoodcompanies.com


Reg. Date : 2012.07.24 16:03
Sex Hormones Linked to Metabolism, Genetic Study
Views : 5961 

New research shows that there is a genetic connection between metabolic functions and reproductive functions in both men and women.

The study, conducted by an international team of scientists has found genetic marker that influences protein called sex hormone-binding globulin (SHBG) in the blood stream. This protein is responsible for regulation of estrogen and testosterone in human blood stream.


Sex hormone-binding globulin (SHBG) is a protein mainly secreted by the liver that binds to sex hormones in the body and transports them in the blood stream, researchers said. SHBG influences the sexual characteristics of men and women.

SHBG has also been linked to various diseases like diabetes type-2 and certain types of cancers like breast and prostate cancer that are dependent on sex-hormones.

For the study, researchers analyzed genomes 21,791 men and women to see what genes are responsible for SHBG functions. They identified 12 single-nucleotide polymorphisms (SNPs) that were bound to the circulating SHBG in the blood stream.

Researchers validated their results by studying genomes of another 7,046 men and women. They found that the genetic variations for this protein occurred more in men than in women.

They also found that the genetic markers for SHBG were present near genes that influence fat, carbohydrate metabolism and even diabetes type 2 in humans According to researchers, the fact that these genes (metabolism and reproduction) are close together may explain why there is a difference in the onset of certain diseases in men and women.

"These findings underscore the connection between the reproductive system and metabolism in both men and women, and may help explain sex differences observed in some metabolic diseases, particularly type 2 diabetes," said Dr. Andrea D. Coviello, assistant professor of medicine at BUSM, endocrinologist at Boston Medical Center and one of the lead authors of the study, in a press release.

Single-nucleotide polymorphisms (pronounced as "snips") are variations that occur in DNA when a single nucleotide in the genomic sequence is altered. SNPs are studied because scientists believe that these variations will help them find multiple genes associated with cancer, diabetes, heart disease among many others.

The study is published in the journal PLoS ONE Genetics.

Original Post from: http://www.medicaldaily.com/news/20120721/11009/sex-hormones-metabolism-genetics.htm

Total 125
125 An A+ Brain!  10-11 5849
124 Turmeric Improves Blood Glucose in Type 2 Diabetes  09-10 5883
123 4 Healthy Habits Stop Cancer, Diabetes, and Heart Disease   07-30 5891
122 Diabetes mellitus may boost pancreatic cancer risk  07-30 5887
121 Like curry? It could help cut your diabetes risk  07-30 5879
120 Diabetes News: Native Americans Ate 16 Times More Fiber than People Today   07-26 5903
119 Exercise Still Cuts Diabetes Risk  07-26 5878
118 Study Suggests That High Doses Of Vitamin D May Prevent Bone Fractures  07-25 5846
117 Women with diabetes more likely to experience sexual dissatisfaction   07-25 5866
116 Weight loss boosts sex life of obese men: study  07-25 5980
115 Best exercise to avoid diabetes study  07-25 5902
114 Diet and Exercise Help With the Weighty Issues of Pregnancy  07-25 5893
113 Vitamin-mineral mix helps slow impact of macular degeneration  07-25 6072
112 A single pill could treat Alzheimer's, Parkinson's AND multiple sclerosis  07-25 5884
111 Iron Deficiency in Children Due to a Certain Combination of Risk Factors  07-25 5900
110 Sex Hormones Linked to Metabolism, Genetic Study   07-24 5961
109 Fig Leaves Used to Treat Diabetes   07-24 5863
108 Cheese Will Make You Happy, May Also Lower Diabetes Risk  07-24 5908
107 FDA approves weight-loss drug  07-23 6044
106 10 Common Food Combinations That Wreak Havoc on Your Health  07-23 6053
 1  2  3  4  5  6  7  
    Eastwood Bio-Medical Research Inc. Unit 1130-4871 Shell Road Richmond, B.C. Canada, V6X 3Z6
Tel: 604.247.2100 or 1.888.669.4372      Email: info@eastwoodcos.com
Copyright© 2011 Eastwood Companies